There are few roads in the Midwest that compare to riding along the Mississippi River between Alton, IL and Grafton, IL on Highway 100. Whether you head North or South, the views are amazing with the countries largest river on one side and gorgeous towering bluffs on the other. A stop in the Grafton, IL river community us a must, with bars, eateries, wineries, zip lines and more waiting for visitors who discover this gem of a river town. Illinois is more than just Chicago and farm fields. Make sure and get this route on your radar if you want to experience motorcycle riding at its finest in the Land of Lincoln.